______________________________________________________________________________________________________________________________________________________________________________________________________________

主要研究领域：

生物钟是植物内在的时间调控机制，能够帮助植物预测和适应环境变化。它不仅协调昼夜交替的生物学过程（Daily），还通过测量光照时间的长短（光周期）来调节季节性生长和发育（Seasonal），从而帮助植物更好地适应环境变化、优化资源利用效率。实验室以水稻和大豆为研究对象，重点开展以下两个方向的研究：（1）生物钟如何与蛋白质降解系统协作，调控作物在昼夜交替过程中生物过程的节律性（Daily）；（2）作物如何通过生物钟感知光周期并响应季节变化（Seasonal）。实验室希望通过这两个方面的研究，全面、系统地解析植物内在时间机制及其与环境信号的互作网络，为培育具有区域适应性和优质高产的作物新品种提供依据。

教育经历：

        2004-2008年，曲阜师范大学，生命科学学院，学士；

        2008-2013年，中山大学，生命科学学院，博士。

工作经历：

        2013年-2015年，中山大学，生命科学学院，博士后；

        2015年-2020年，美国耶鲁大学，分子细胞发育生物学系，博士后；

        2020年-2024年，美国耶鲁大学，分子细胞发育生物学系，副研究员；

        2025年-至今，华南农业大学，农学院，首聘教授、博导。

论文著作 (*co-first author)      

1. Liu, W*., Lowrey, H*., Leung, C.C., Adamchek, C., Du, J., He, J., Chen, M., and Gendron, J.M. (2024). A circadian clock output functions independently of phyB to sustain daytime PIF3 degradation. Proc Natl Acad Sci U S A 121(35):e2408322121.

2. Wang, Q., Liu, W., Leung, C.C., Tarte, D.A., and Gendron, J.M. (2024). Plants distinguish different photoperiods to independently control seasonal flowering and growth. Science 383, eadg9196.

-Highlighted by Buckley and Haydon (2024) Time for Growth. Science 383(6683):589-590.

3. Wang, Y.H., Liu, W., Cheng, J., Li, R.J., Wen, J., Mysore, K.S., Xie, Z.P., Reinhardt, D., and Staehelin, C. (2023). An extracellular β-N-acetylhexosaminidase of Medicago truncatula hydrolyzes chitooligosaccharides and is involved in arbuscular mycorrhizal symbiosis but not required for nodulation. New Phytol.239, 1954-1973.

4. Sepulveda, C., Guzman, M.A., Li, Q., Villaecija-Aguilar, J.A., Martinez, S.E., Kamran, M., Khosla, A., Liu, W., Gendron, J.M., Gutjahr, C., Waters, M.T., and Nelson, D.C. (2022). KARRIKIN UP-REGULATED F-BOX 1 (KUF1) imposes negative feedback regulation of karrikin and KAI2 ligand metabolism in Arabidopsis thaliana. Proc Natl Acad Sci U S A119, e2112820119.

5. Liu, W., Feke, A., Leung, C.C., Tarté, D.A., Yuan, W., Vanderwall, M., Sager, G., Wu, X., Schear, A., Clark, D.A., Thines, B.C., and Gendron, J.M. (2021). A metabolic daylength measurement system mediates winter photoperiodism in plants. Dev. Cell 56(17):2501-2515.e5.

6. Gendron, J.M., Leung, C.C., and Liu, W. (2021). Energy as a seasonal signal for growth and reproduction. Curr. Opin. Plant Biol. 63, 102092.

7. Feke, A., Vanderwall, M., Liu, W., and Gendron, J.M. (2021). Functional domain studies uncover novel roles for the ZTL Kelch repeat domain in clock function. PloS One16, e0235938.

8. Liu, W. and Gendron, J.M. (2020). Same Concept Different Outcomes: Sugars Determine Circadian Clock Protein Fate in Animals and Plants. Mol. Plant 13:360–362.

9. Feke, A.M., Hong, J., Liu, W., and Gendron, J.M. (2020). A Decoy Library Uncovers U-Box E3 Ubiquitin Ligases That Regulate Flowering Time in Arabidopsis. Genetics. 215(3):699–712.

10. He, L., Lei, Y., Li, X., Peng, Q., Liu, W., Jiao, K., Su, S., Hu, Z., Shen, Z., and Luo, D. (2020) Symmetric petals 1 encodes an ALOG domain protein that controls floral organ internal asymmetry in pea (Pisum sativum L.). Int. J. Mol. Sci. 21(11):1–15.

11. Feke, A., Liu, W., Hong, J., Li, M.-W., Lee, C.-M., Zhou, E.K., and Gendron, J.M. (2019). Decoys provide a scalable platform for the identification of plant E3 ubiquitin ligases that regulate circadian function. eLife 8, e44558.

12. Li, X*., Liu, W*., Zhuang, L., Zhu, Y., Wang, F., Chen, T., Yang, J., Ambrose, M., Hu, Z., Weller, J., and Luo, D. (2019). BIGGER ORGANS and ELEPHANT EAR-LIKE LEAF1 control organ size and floral organ internal asymmetry in pea. J. Exp. Bot.70(1), 179–191.

13. Lee, C.-M., Li, M.-W., Feke, A., Liu, W., Saffer, A.M., and Gendron, J.M. (2019). GIGANTEA recruits the UBP12 and UBP13 deubiquitylates to regulate accumulation of the ZTL photoreceptor complex. Nat. Commun.10(1), 3750.

14. Li, M.-W., Liu, W., Lam, H.-M., and Gendron, J.M. (2018). Characterization of Two Growth Period QTLs Reveals Modification of PRR3 Genes During Soybean Domestication. Plant Cell Physiol. 60(2), 407–420.

15.  Cai, J., Zhang, L.-Y., Liu, W., Tian, Y., Xiong, J.-S., Wang, Y.-H., Li, R.-J., Li, H.-M., Wen, J., Mysore, K.S., Boller, T., Xie, Z.-P., and Staehelin, C. (2018). Role of the Nod Factor Hydrolase MtNFH1 in Regulating Nod Factor Levels during Rhizobial Infection and in Mature Nodules of Medicago truncatula. Plant Cell 30(2), 397– 414.

16.  Liu, Y.C., Lei, Y.W., Liu, W., Weng, L., Lei, M.J., Hu, X.H., Dong, Z.C., Luo, D., and Yang, J. (2018). LjCOCH interplays with LjAPP1 to maintain the nodule development in Lotus japonicus. Plant Growth Regul. 85, 267-279.

17.  Zhang, L.-Y., Cai, J., Li, R. J., Liu, W., Wagner, C., Wong, K. B., Xie, Z.-P., and Staehelin, C. (2016). A single amino acid substitution in a chitinase of the legume Medicago truncatula is sufficient to gain Nod factor hydrolase activity. Open Biol. 6(7).

18.  Tian, Y*., Liu, W*., Cai, J., Zhang, L.-Y., Wong, K.-B., Feddermann, N., Boller, T., Xie, Z.iP., and Staehelin, C. (2013). The Nodulation Factor Hydrolase of Medicago truncatula: Characterization of an Enzyme Specifically Cleaving Rhizobial Nodulation Signals. Plant Physiol.163(3), 1179 – 1190.

承担科研项目情况：

1. 华南农业大学高层次引进人才项目（拔尖人才）项目，2025-2028年，主持；

 2. 中国博士后科学基金面上资助（一等)，2014-2015年，主持。

    实验室诚聘博士后1-2名，欢迎具有生物学及相关领域研究背景的优秀博士申请。