Qiupeng Lin
Title：Professor
Address: Room 201, College of Agriculture, South China Agricultural University, Guangzhou
Email:qiupenglin@scau.edu.cn
RESEARCH INTEREST
1. Developing and optimizing novel CRISPR technologies for precise genome editing.
2. Applying high-throughput for effector discovery to develop novel CRISPR precise editing
systems
3. Applying new genome editing tools for therapeutic and agricultural applications.
EDUCATION
2017.09-2021.07 PhD in Genetics, Institute of Genetics and Developmental Biology, Chinese
Academy of Sciences
2014.09-2017.07 M.Sc. in Botany, School of Life Science, South China Normal University
2010.09-2014.07 B.Sc. in Life Science (Xiangqin Class), School of Life Science, South China Normal University
EMPLOYMENT HISTORY
2023.07-present Professor, College of Agriculture, South China Agricultural University
2021.06-2023.06 Postdoctoral Fellow, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
AWARDS AND HONORS
2021 Fellowship of China National Postdoctoral Program for Innovative Talents
2020 National scholarship for doctoral students
2020 President Excellence Scholarship of Chinese Academy of Sciences
2020 Zhensheng Scholarship
PUBLICATIONS
[1]Lin, Q.1, Zong, Y.1, Xue, C.1, Wang, S., Jin, S., Zhu, Z., Wang, Y., Anzalone, A.V.,
Raguram, A., Doman, J.L., Liu, D.R., and Gao, C.* (2020). Prime genome editing in rice
and wheat. Nat. Biotechnol. 38, 582-585. (IF2020=54.9) (329 citations) (F1000Primerecommended paper, highlighted by Trends in Plant Science)
[2]Lin, Q.1, Jin, S.1, Zong, Y.1, Yu, H.1, Zhu, Z., Liu, G., Kou, L., Wang, Y., Qiu, J.L., Li, J.*,
and Gao, C.* (2021). High-efficiency prime editing with optimized, paired pegRNAs in
plants. Nat. Biotechnol. 39, 923-927. (IF2021=68.2) (Highlighted by Nature Methods)
[3]Huang, J.1, Lin, Q.1, Fei, H.1, He, Z.1, Xu, H., Li, Y., Qu, K., Han, P., Gao, Q., Li, B., Liu, G., Zhang, L., Hu, J., Zhang, R., Luo, Y., Ran, Y., Qiu, J.L., Zhao, K. T.*, and Gao, C.* (2023). Discovery of deaminases functions by structure-based protein clustering. Cell 186, 3182-3195.e14. (IF2023=45.6) (China's top 10 science advances in 2023, Best of Cell 2023, China's top 10 bioinformatics advances in 2023, China's major agricultural scienceadvances in 2024, F1000Primerecommended paper, highlighted by Trends in Plant Science, Science Bulletin, and Signal Transduction and Targeted Therapy)
[4]Jin, S.1, Lin, Q.1, Luo, Y.1, Zhu, Z.1, Liu, G., Li, Y., Chen, K., Qiu, J.L., and Gao, C. (2021).
Genome-wide specificity of prime editors in plants. Nat. Biotechnol. 39, 1292-1299.
(IF2021=68.2) (Highlighted by Nature Methods)
[5]Wang, S.1, Zong, Y.1, Lin, Q.1, Zhang, H.1, Chai, Z., Zhang, D., Chen, K., Qiu,J.L., and
Gao, C. (2020). Precise, predictable multi-nucleotide deletions in rice and wheat using
APOBEC-Cas9. Nat. Biotechnol. 38, 1460-1465. (IF2020=54.9)
[6]Jin, S.1, Lin, Q.1, and Gao, C. (2022). A method for optimized prime editing and
application in plants. Nat. Protoc. (Invited paper, accepted). (IF2021=17.0)
[7]Liu, G.1, Lin, Q.1, Jin, S.1, and Gao, C. (2022). The CRISPR-Cas toolbox and gene
editing technologies. Mol. Cell 82, 333-347. (IF202=19.3)
[8]Xu, Y.1, Lin, Q.1, Li, X., Wang, F., Chen, Z., Wang, J., Li, W., Fan, F., Tao, Y., Jiang, Y.,
Wei, X., Zhang, R., Zhu, Q.H., Bu, Q., Yang, J., and Gao, C. (2021). Fine-tuning the
amylose content of rice by precise base editing of the Wx Gene. Plant Biotechnol. J. 19,
11-13. (IF2021=13.3)
[9]Lin, Q.1, Zhu, Z.1, Liu, G.1, Sun, C., Lin, D., Xue, C., Li, S., Zhang, D., Gao, C., Wang, Y.,
and Qiu, J.L. (2021). Genome editing in plants with MAD7 nuclease. J. Genet. Genomics.
48, 444-451. (IF2021=5.7) (Cover story)
[10]Lin, Q.1, Zhou, Z.1, Luo, W., Fang, M., Li, M., and Li, H. (2017). Screening of proximal
and interacting proteins in rice protoplasts by proximity-dependent biotinylation. Front.
Plant Sci. 8, 749. (IF2017=3.7)
[11]Xu, J.J., Lei, Y., Zhang, X.F., Li, J.X., Lin, Q., Wu, X.D., Jiang, Y.G., Zhang, W., Qian, R., Xiong, S.Y., Tan, K., Jia, Y., Zhou, Q., Jiang, Y., Fan, H., Huang, Y.B., Wang, L.J., Liu, J.Y., Kong, Y., Zhao, Q., Yang, L., Liu, J., Hu, Y.H., Zhan, S., Gao, C.*, and Chen, X.Y.* (2025). Design of CoQ10 crops based on evolutionary history. Cell 188, 1941-1954.e15.
[12]Jiang, Y.1, Chai, Y.1, Lu, M.1, Han, X., Lin, Q., Zhang, Y., Zhang, Q., Zhou, Y., Wang, X.,
Gao, C., and Chen, Q.J. (2020). Prime editing efficiently generates W542L and S621I
double mutations in two ALS genes in maize. Genome Biol. 21, 257.
[13]Xue, C.1, Zhang, H.1, Lin, Q., Fan, R., and Gao, C. (2018). Manipulating mRNA splicing
by base editing in plants. Sci. China Life Sci. 61, 1293-1300.
[14]Li, M.1, Li, X.1, Zhou, Z., Wu, P., Fang, M., Pan, X., Lin, Q., Luo, W., Wu, G.*, and Li, H.*
(2016). Reassessment of the Four Yield-related Genes Gn1a, DEP1, GS3, and IPA1 in Rice
Using a CRISPR/Cas9 System. Front. Plant Sci. 7, 377.
[15]Gao, H., Pei, X., Song, X., Wang, S., Yang, Z., Zhu, J., Lin, Q.*, Zhu Q*, and Yang X.*(2025). Application and development of CRISPR technology in the secondary metabolic pathway of the active ingredients of phytopharmaceuticals. Front Plant Sci.15, 1477894.
[16]Zhang, R., Chai, N., Liu, T., Zheng, Z., Lin, Q., Xie, X., Wen, J., Yang, Z., Liu, Y.G.*, and Zhu, Q.* The type V effectors for CRISPR/Cas-mediated genome engineering in plants. Biotechnol. Adv.74:108382.
[17]Liu, J., Zhang, R., Chai, N., Su, L., Zheng, Z., Liu, T., Guo, Z., Ma, Y., Xie, Y., Xie, X., Lin, Q., Chen, L., Liu, Y.G.*, and Zhu, Q.*(2025). Programmable genome engineering and gene modifications for plant biodesign. Plant Commun. 24,101427.